Each tribe has its own legend or story about how they came to use Kambo. Although, the most accredited originator of the Kambo legend is the Kaxinawá tribe from Brazil. As legend has it, many of the Kaxinawá tribesmen were extremely ill and this time, not even, their medicine man, (Pajé in Brazil), could treat them. He administered all the medicinal herbs at his disposal, sought his ancestors for counsel, and performed shamanic rituals. Paje expended all of his resources yet proved unsuccessful. Then one day, he consumed sacred plant medicines and received guidance. He was instructed to enter deep into the forest where he was visited by, what is referred to as, the female spirit of the forest. This great female spirit revealed to Paje the Kambo frog and taught him how to extract and administer the white secretion. Thereafter, Paje trekked back to the tribe and, finally, cured his tribesman of all their health conditions. In recognition for saving the Kaxinawá people, from then on he was revered as Pajé Kampu or Kampum.  After his passing, it is understood that his spirit remains to live in the frog to continue its mission to protect the health of those who defend the forest.